Peer Reviewed
Perspectives
Clinical implications of erectile dysfunction: a new paradigm in the investigation for cardiovascular risk
Abstract
Erectile dysfunction is a novel marker and predictor for future atherosclerotic cardiovascular events.
Key Points
- Erectile dysfunction (ED) is a novel marker and predictor for future atherosclerotic cardiovascular (CV) events and death due to CV causes.
- Atherosclerosis resulting from dysfunction of the vascular endothelium is common to both ED and CV disease (CVD).
- Atherosclerotic changes are likely to be evident earlier in arteries of smaller calibre, such as those in the penile vasculature, than in the larger arteries of the coronary circulation.
- In spite of their increased risk of death due to CV causes, almost as many men with ED die from cancers as from CV causes, and these cancer deaths occur sooner.
- Rigorous investigation of men with ED provides information on their individual CV risk and opportunities for its early minimisation.
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