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Sunday 5 July 2026

Peer Reviewed

Case studies

Statin-associated muscle adverse events: some key issues explored

Leon A Simons

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Recent articles on:
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Statin-associated muscle adverse events: some key issues explored

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Abstract

Muscle symptoms and signs often represent an important adverse event associated with statin therapy.

Key Points

Muscle symptoms and signs are the most frequent adverse events associated with statin therapy.
These adverse events occur more frequently in routine care than in controlled clinical trials.
Alternative causes must be excluded.
Less frequent-than-daily dosing with another statin at a low dose may overcome muscle problems in some instances.
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